By Eliza I. Swahn
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Extra info for Diabetes in Women (Public Health in the 21st Century)
Short duration) and not too severe DM-2 with appropriate care in our study. GDM did also not associate with a higher risk of total CAs explained mainly with its onset after the third gestational month. However the possible association of GDM with a higher risk of obstructive CAs of urinary tract needs further studies. 5-fold instead of the previous 4 to 8-fold) and the lack of higher risk of neural-tube defects and the 20 Andrew E. Czeizel, Nándor Ács and Ferenc Bánhidy lower risk of some other specific DM-1 related isolated CA reflect the recent progress in the specific prenatal care of diabetic pregnant women including folic acid supplementation.
Liverspecific IGF-I gene-null mice reveals a marked reduction in bone volume, periosteal circumference, and medial lateral width, suggesting that circulating levels of IGF-I also directly regulate bone growth and density (60). Indeed, our clinical studies showed that serum IGF-I levels were positively associated with BMD and inversely with the risk of vertebral fractures in postmenopausal Markers for Assessing Bone Condition in Women… 31 women without diabetes (61,62). These findings suggest that serum IGF-I levels could be clinically useful for assessing bone mass and the risk of vertebral fractures in the non-diabetic population.
15] Czeizel AE, Evans JA, Kodaj I, Lenz W: Congenital Limb Deficiencies in Hungary. Genetic and Teratologic Epidemiological Studies. Akadémiai Kiadó, Budapest, 1994.  Czeizel AE, Intõdy Zs, Modell B: What proportion of congenital abnormalities can be prevented? Brit Med J. 1993; 306: 499-503.  Czeizel AE, Petik D, Vargha P: Validation studies of drug exposures in pregnant women. Pharmacoepid Drug Safety, 2003; 12: 409-416.  Czeizel AE, Puhó E, Bánhidy F: No association between periconceptional multivitamin supplementation and risk of multiple congenital abnormalities.
Diabetes in Women (Public Health in the 21st Century) by Eliza I. Swahn